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Watch the clock: Heart attacks in the morning are more severe

Severeness of afflictions ranging from allergies to heart attacks differs in the morning from that in the night.

ANI|
May 18, 2019, 05.38 PM IST
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WASHINGTON DC: While sickness comes irrespective of the time, the severeness of afflictions ranging from allergies to heart attacks differs in the morning from that in the night, highlighted a new study.

The study was published in the Journal Trends in Immunology which compiled studies, predominantly in mice, that looked at the connection between circadian rhythms and immune responses.

The body reacts to cues such as light and hormones to anticipate recurring rhythms of sleep, metabolism, and other physiological processes. The numbers of white blood cells, in both humans and mice also oscillate in a circadian manner.

Taking into account the above-mentioned facts, researchers in the study found that:

Heart attacks in humans are known to strike most commonly in the morning, and research suggests that morning heart attacks tend to be more severe than at night.

Cut Down On Salt, Drink Fluids: Simple Diet Tips To Avoid Chronic Heart Failure

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Save Your Heart

29 Sep, 2018
Cardiac or heart failure is a clinical condition in which the heart loses the ability to eject blood to meet the requirements of the tissues of the body. Irrespective of the cause, nutritional concerns need to be addressed in this condition in order to prevent morbidity and mortality. Patients with chronic heart failure are at constant risk of losing weight due to the medical condition and also low dietary intake which is due poor appetite, depression or loss of appetite due to consumption of drugs.Dietary interventions to maintain and restore the nutritional balance are essential part of treatment therapy. These include a suitable change in calorie intake, reduction in sodium and fluid intake, maintenance of potassium and magnesium in the body, and appropriate supplementation with vitamins and minerals.Here are some simple tips by Dr Ritika Samaddar, Chief Nutritionist at Max Hospital, Saket.
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In mice, the numbers of monocytes--a type of white blood cell that fights off bacteria, viruses, and fungi--are elevated in the blood during the day. At night, monocytes are elevated in infarcted heart tissue, resulting in decreased cardiac protection at that time of day relative to morning.

Parasite infections are time-of-day dependent. Mice infected with the gastrointestinal parasite Trichuris muris in the morning have been able to kill worms significantly faster than those infected in the evening.

Allergic symptoms follow a time-of-day dependent rhythmicity, generally worse between midnight and early morning. Hence, the molecular clock can physiologically drive innate immune cell recruitment and the outcomes of asthma in humans, or airway inflammation in mice--the review notes.

"Investigating circadian rhythms in innate and adaptive immunity is a great tool to generally understand the physiological interplay and time-dependent succession of events in generating immune responses," said senior author Christoph Scheiermann, University of Geneva.
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